nerdlinger wrote: ↑Mon Oct 11, 2021 8:11 pm

timmydownawell wrote: ↑Mon Oct 11, 2021 6:06 pm
When you say "Intuitively it feels like mixing shots would give better protection from variants" then yes, that is how I feel, rightly or wrongly.

My amateur doctor reasoning on why it might not be the case is that it’s not the vaccine itself that kills the coronavirus, it’s your immune system’s response to the vaccine. So, it doesn’t necessarily follow that two different vaccines based on the same coronavirus would breed two unique and complementary sets of antibodies in the same person.

(Caution: all the above may be bollocks and probably is)

LionelBurns wrote: ↑Tue Oct 12, 2021 10:33 am First it was the PP mayor on OTT restrictions. Then the governor stepped in so as not to be outdone to make his high water wall mark in the pissin contest.

clutchcargo wrote: ↑Mon Oct 11, 2021 5:08 pm

timmydownawell wrote: ↑Mon Oct 11, 2021 4:26 pm

clutchcargo wrote: ↑Mon Oct 11, 2021 3:44 pm

timmydownawell wrote: ↑Mon Oct 11, 2021 2:26 pm

clutchcargo wrote: ↑Mon Oct 11, 2021 1:11 pm ^^
Might have got buried in another thread, but there's also info here for getting a Sinovac booster post516297.html#p516297

Which raises the question: If one has already had 2 Sinovac shots, should they get another Sinovac booster or an AZ booster?

I believe getting AZ would improve your overall protection because it's a different type of vaccine. i.e you'd have a broader protection than Sinovac alone. If you think back several months they were trialling mix'n'match shots for that exact reason. Early trials of one AZ plus one Pfizer were quite promising.

https://www.reuters.com/world/middle-ea ... 021-05-24/

I looked specifically for studies on the effects of mixing Sinovac and another vaccine booster. Turkey and Thailand have/are doing that.

Some results from Turkey suggests 3 shots of Sinovac are better than mixing Sinovac/Pfizer ie 3 doses of inactive vaccines, rather than in those who received two doses of inactive vaccines and one booster shot of an mRNA vaccine (the rest of the article is pay walled). As AZ is an inactive vaccine, maybe that's OK too?
https://asia.nikkei.com/Spotlight/Coron ... h-minister

There seems to be no study results yet on mixing Sinovac and AZ even though the governments of Turkey, Thailand and Cambodia say it's OK to do. Plus in some countries AZ is not recommended for young people.

Well obviously the authorities here have decided to go this way. They're reserving what's left of the AZ for third shots only. I mean, if you'd prefer a third Sinovac instead, just wait a month or two longer for them to run out of AZ. They got in 6m more doses of Sinovac so I'm not sure what that's for if not third shots.

I'm not trying to be argumentative, but honestly I'm not clear what the way of the authorities is. On the one hand, you have HE announcing Sinovac should be mixed with AZ, yet OTOH you have the PP MOH progressing with the Sinovac booster rollout to-day and the 30th. So together with the National Pedriatic and Preah Ang Doung Hospitals issuing AZ, you've got 2 rollouts running in tandem with no guidance on which one individuals should choose. However, it seems they may not have enough of the AZ booster so it'll be a case of reverting to the Sinovac booster.

Maybe it's no big deal and people can just choose.. For me personally tho, to make a decision which way to go, I would have liked to see some reports or results of mixing Sinovac and AZ (other than politicians saying it's OK). Maybe I'm being overly cautious I dunno.

LionelBurns wrote: ↑Tue Oct 12, 2021 2:06 pm Yongchi: Look up/googl adenovirus, adenovirus vaccines and then the J&J.
"An adenovirus vaccine is a vaccine against adenovirus infection. It was used by the United States military from 1971 to 1999, but was discontinued when the only manufacturer stopped production" I would much rather take a chance on a vaccine that's been around for a long time than something new that doesn't have a track record yet. The bioNtec is being tried for Covid-19 only and therefore hasn't been tested except on humans. There is a wealth of diseases that adenovirus vaccines have been used on including TB, HIV, Tetanus, diphtheria, measles, mumps, the poxes, etc. The only viruses that need boosters are Tetanus and diphtheria. Every 10 years for Tetanus. I've been way down the rabbit hole on this one.