Chinese Vaccine is a Bloody Joke

yong · Post by **yong** » Wed Jan 13, 2021 3:55 pm

The Pfizer vaccine showed efficacy of 95%
The Moderna vaccine was 94.1%
Sinovac is 50.4% - dafug?

https://asia.nikkei.com/Spotlight/Coron ... razil-data

Sinovac vaccine disappoints at 50.4% efficacy: latest Brazil data
Results come as scientists slam biomed center for raising 'unrealistic' hopes

The Butantan biomedical production center in Sao Paulo, Brazil, is being blasted by scientists and observers for releasing partial data only days ago that generated unrealistic expectations. © Reuters
January 13, 2021 10:34 JST

SAO PAULO (Reuters) -- A coronavirus vaccine developed by China's Sinovac Biotech was just 50.4% effective at preventing symptomatic infections in a Brazilian trial, researchers said on Tuesday, barely enough for regulatory approval and well below the rate announced last week.

The latest results are a major disappointment for Brazil, as the Chinese vaccine is one of two that the federal government has lined up to begin immunization during the second wave of the world's second-deadliest COVID-19 outbreak.

Several scientists and observers blasted the Butantan biomedical center for releasing partial data just days ago that generated unrealistic expectations. The confusion may add to skepticism in Brazil about the Chinese vaccine, which President Jair Bolsonaro has criticized, questioning its "origins."

"We have a good vaccine. Not the best vaccine in the world. Not the ideal vaccine," said microbiologist Natalia Pasternak, criticizing Butantan's triumphant tone.

Last week, the Brazilian researchers had celebrated results showing 78% efficacy against "mild-to-severe" COVID-19 cases, a rate they later described as "clinical efficacy."

They said nothing at the time about another group of "very mild" infections among those who received the vaccine that did not require clinical assistance.

Ricardo Palacios, medical director for clinical research at Butantan, said on Tuesday that the new lower efficacy finding included data on those "very mild" cases.

"We need better communicators," said Gonzalo Vecina Neto, a professor of public health at the University of Sao Paulo and former head of Brazilian health regulator Anvisa.

Piecemeal disclosures about Chinese vaccine trials globally have raised concerns that they are not subject to the same public scrutiny as U.S. and European alternatives.

Palacios and officials in the Sao Paulo state government, which funds Butantan, emphasized the good news that none of the volunteers inoculated with CoronaVac had to be hospitalized with COVID-19 symptoms.

Public health experts said that alone will be a relief for Brazilian hospitals that are buckling under the strain of surging case loads. However, it will take longer to curb the pandemic with a vaccine that allows so many mild cases.

"It's a vaccine that will start the process of overcoming the pandemic," Pasternak said.

Researchers at Butantan delayed announcement of their results three times, blaming a confidentiality clause in a contract with Sinovac.

In the meantime, Turkish researchers said last month that CoronaVac was 91.25% effective based on an interim analysis. Indonesia gave the vaccine emergency use approval on Monday based on interim data showing it is 65% effective.

Butantan officials said the design of the Brazilian study, focusing on frontline health workers during a severe outbreak in Brazil and including elderly volunteers, made it impossible to compare the results directly with other trials or vaccines.

Still, COVID-19 vaccines in use from Pfizer Inc with partner BioNTech SE and Moderna Inc proved to be about 95% effective in preventing illness in their pivotal late-state trials.

The disappointing CoronaVac data is the latest setback for vaccination efforts in Brazil, where more than 200,000 people have died since the outbreak began - the worst death toll outside the United States.

Brazil's national immunization program currently relies on CoronaVac and the vaccine developed by Oxford University and AstraZeneca Plc - neither of which has received regulatory approval in Brazil.

Anvisa, which has stipulated an efficacy rate of at least 50% for vaccines in the pandemic, has already pressed Butantan for more details of its study, after it filed for emergency use authorization on Friday.

The regulator said it will meet on Sunday to decide on emergency use requests for CoronaVac and the British vaccine.

AstraZeneca failed to deliver active ingredients to Brazil over the weekend, leaving the government scrambling to import finished doses of the vaccine from India to begin inoculations.

ExPenhMan · Post by **ExPenhMan** » Wed Jan 13, 2021 5:07 pm

The fact that none of the Chinese vaccine developers have released full data sets on any of their trial stages and the fact that the Brazilians had their hands tied by a "confidentiality clause" . . .

Researchers at Butantan delayed announc ... h Sinovac.

. . . says all you need to know about China's own lack of confidence (and mine too) in the Chinese vaccine candidates.

Also: China’s vaccines are poised to help less wealthy nations, but face trust issues

China has six candidates in the last stage of trials and is one of the few nations that can manufacture vaccine on a large scale. Government officials have announced a capacity of 1 billion doses next year, with President Xi Jinping vowing China’s vaccines will be a boon to the world.

The potential use of its vaccine by millions of people in other countries gives China an opportunity both to repair the damage to its reputation from an outbreak that escaped its borders and to show the world it can be a major scientific player.

Yet past scandals have damaged its own citizens’ trust in its vaccines, with manufacturing and supply chain problems casting doubt on whether it can really be a savior.

“A question mark remains over how China can ensure the delivery of reliable vaccines,” said Joy Zhang, a professor who studies the ethics of emerging science at the University of Kent in Britain. She cited China’s “non-transparency over scientific data and a troubled history with vaccine delivery.”

https://www.cnbc.com/2020/12/25/chinas- ... ssues.html

Alex · Post by **Alex** » Wed Jan 13, 2021 6:03 pm

That's just horrible, I'd rather have a saline injection. Cheaper, safer and about as (in) effective!

Bitte_Kein_Lexus · Post by **Bitte_Kein_Lexus** » Wed Jan 13, 2021 6:34 pm

Wait for this news to be blocked in China...

newkidontheblock · Post by **newkidontheblock** » Wed Jan 13, 2021 7:46 pm

China vaccine uses virus, vs. focusing an immune response on the mechanism that causes infection. The virus has mutated many times already, thus no longer looking exactly like the original.

Think flu vaccine.

The scientists went for tried and true methods. Create a flu vaccine. They did as ordered.

John Bingham · Post by **John Bingham** » Wed Jan 13, 2021 8:06 pm

yong wrote: ↑Wed Jan 13, 2021 3:55 pm "We have a good vaccine. Not the best vaccine in the world. Not the ideal vaccine," said microbiologist Natalia Pasternak

Is it wrong that I found this hilarious? Am I bad?

CEOCambodiaNews · Post by **CEOCambodiaNews** » Wed Jan 13, 2021 9:29 pm

John Bingham wrote: ↑Wed Jan 13, 2021 8:06 pm
yong wrote: ↑Wed Jan 13, 2021 3:55 pm "We have a good vaccine. Not the best vaccine in the world. Not the ideal vaccine," said microbiologist Natalia Pasternak
Is it wrong that I found this hilarious? Am I bad?

Yep.

emm · Post by **emm** » Thu Jan 14, 2021 9:10 pm

This makes me laugh !
Who on this planet REALLY knows how EFFECTIVE other Vaccines really are ? In "Normal" Times Vaccines take years to develop.
Now it just took 9 month and MIRACLE is there. When we look back (those that survive the pandemic) we will really know how EFFECTIVE which kind of Vaccine really WAS !
Up until than it's just big Business and a reason to implement supressive measures on citizens around the world that would have been very difficult to push through in such a quick time. Do i believe Covid 19 is a real threat to humanity . YES and YES again. But the way Humanity lives it was obvious it had to happen sooner or later. Perhaps Viruses are much smarter than Humans ?

IraHayes · Post by **IraHayes** » Thu Jan 14, 2021 10:27 pm

emm wrote: ↑Thu Jan 14, 2021 9:10 pm This makes me laugh !
Who on this planet REALLY knows how EFFECTIVE other Vaccines really are ? In "Normal" Times Vaccines take years to develop.
Now it just took 9 month and MIRACLE is there. When we look back (those that survive the pandemic) we will really know how EFFECTIVE which kind of Vaccine really WAS !
Up until than it's just big Business and a reason to implement supressive measures on citizens around the world that would have been very difficult to push through in such a quick time. Do i believe Covid 19 is a real threat to humanity . YES and YES again. But the way Humanity lives it was obvious it had to happen sooner or later. Perhaps Viruses are much smarter than Humans ?

It's called "science" and it never stands still.

https://www.nature.com/articles/d41586-020-03626-1

The above article may help you to understand how a vaccine was developed in such a short time. Rapid vaccine development isn't unusual either and the ebola vaccine was given FDA approval in 5 years from the 1st clinical trials.

oh and ....

Perhaps Viruses are much smarter than Humans ?

I'd say they are certainly smarter than some humans.

nerdlinger · Post by **nerdlinger** » Fri Jan 15, 2021 3:26 am

Alex wrote: ↑Wed Jan 13, 2021 6:03 pm That's just horrible, I'd rather have a saline injection. Cheaper, safer and about as (in) effective!

At the start of the pandemic people were praying for 50%. Most flu vaccines are only 50-60%. The only reason it looks so bad is because moderna and Pfizer both managed to turn in 95%.

For sure give me the 95%, but the unfortunate reality is there’s not enough Pfizer to cover the world’s population. 50% on the other hand still gets you pretty close to herd immunity for those countries whose only other option is nothing.

Chinese Vaccine is a Bloody Joke

Chinese Vaccine is a Bloody Joke

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