Resources Coronavirus
Resources Coronavirus
I considered posting this under the main thread, but it has >150 pages.
Many posters have posted very helpful resources in that thread, which are slowly getting buried.
Here is a resource that I feel may be useful for forum members:
Coronavirus Resource Center by Harvard Medical School
https://www.health.harvard.edu/diseases ... rce-center
I have also come across this document:
INTERIM CLINICAL GUIDANCE FOR PATIENTS SUSPECTED OF/CONFIRMED WITH COVID- 19 IN BELGIUM
https://epidemio.wiv-isp.be/ID/Document ... nt_ENG.pdf
Please note that I am not a doctor/medical professional and I don't play one on this forum.
I certainly know less than many other posters on the topic and this is not medical advice!
But I intend to educate myself as well as I can in case I am unable to access medical services here.
Please feel free to add resources as you see fit.
But please, whenever possible, add a reference to the source, so each of us can assess how trustworthy they find the source—and check for updates.
If the administrators of this forum wish to start a dedicated resource thread, that would be even better.
I will be happy to contribute there then.
Many posters have posted very helpful resources in that thread, which are slowly getting buried.
Here is a resource that I feel may be useful for forum members:
Coronavirus Resource Center by Harvard Medical School
https://www.health.harvard.edu/diseases ... rce-center
I have also come across this document:
INTERIM CLINICAL GUIDANCE FOR PATIENTS SUSPECTED OF/CONFIRMED WITH COVID- 19 IN BELGIUM
https://epidemio.wiv-isp.be/ID/Document ... nt_ENG.pdf
Please note that I am not a doctor/medical professional and I don't play one on this forum.
I certainly know less than many other posters on the topic and this is not medical advice!
But I intend to educate myself as well as I can in case I am unable to access medical services here.
Please feel free to add resources as you see fit.
But please, whenever possible, add a reference to the source, so each of us can assess how trustworthy they find the source—and check for updates.
If the administrators of this forum wish to start a dedicated resource thread, that would be even better.
I will be happy to contribute there then.
- truffledog
- Expatriate
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Re: Resources Coronavirus
short list of applied medicines showing some good results (obviously none of them has any certified clinical study yet, but some incouraging results are there): I AM NOT A DOCTOR SO PLEASE DO NOT TAKE ANY OF THEM DRUGS WITHOUT CONSULTING A DOCTOR FIRST
favipiravir (applied in Japan for early stage: https://www.theguardian.com/world/2020/ ... says-china)
tocilizumab (apllied in Italy, actual study:https://www.aifa.gov.it/web/guest/-/aif ... a-covid-19)
remdesivir (https://www.sciencemag.org/news/2020/03 ... treatments)
chloroquine and hydroxychloroquine (https://www.cdc.gov/coronavirus/2019-nc ... tions.html
I am not encouraging anybody to self medicate in case you suspect beeing infected. Please leave it to the doctors to decide which one may be the best for you.
favipiravir (applied in Japan for early stage: https://www.theguardian.com/world/2020/ ... says-china)
tocilizumab (apllied in Italy, actual study:https://www.aifa.gov.it/web/guest/-/aif ... a-covid-19)
remdesivir (https://www.sciencemag.org/news/2020/03 ... treatments)
chloroquine and hydroxychloroquine (https://www.cdc.gov/coronavirus/2019-nc ... tions.html
I am not encouraging anybody to self medicate in case you suspect beeing infected. Please leave it to the doctors to decide which one may be the best for you.
work is for people who cant find truffles
Re: Resources Coronavirus
Some useful links, particularly wrt Favipiravir which showed a 71.43% recovery rate in a Randomized Clinical Trial:truffledog wrote: ↑Tue Mar 24, 2020 3:21 pm short list of applied medicines showing some good results (obviously none of them has any certified clinical study yet, but some incouraging results are there): I AM NOT A DOCTOR SO PLEASE DO NOT TAKE ANY OF THEM DRUGS WITHOUT CONSULTING A DOCTOR FIRST
favipiravir (applied in Japan for early stage: https://www.theguardian.com/world/2020/ ... says-china)
tocilizumab (apllied in Italy, actual study:https://www.aifa.gov.it/web/guest/-/aif ... a-covid-19)
remdesivir (https://www.sciencemag.org/news/2020/03 ... treatments)
chloroquine and hydroxychloroquine (https://www.cdc.gov/coronavirus/2019-nc ... tions.html
I am not encouraging anybody to self medicate in case you suspect beeing infected. Please leave it to the doctors to decide which one may be the best for you.
Favipiravir versus Arbidol for COVID-19: A Randomized Clinical Trial
Results: 120 patients were assigned to favipiravir group (116 assessed) and 120 to arbidol group (120 assessed). In FAS cohort, for ordinary patients with COVID-19, 7 day′s clinical recovery rate was 55.86% in the arbidol group and 71.43% in the favipiravir group (P = 0.0199). For ordinary COVID-19 patients and COVID-19 patients with hypertension and/or diabetes, the time of fever reduction and cough relief in favipiravir group was significantly shorter than that in arbidol group
Check the trial abstract here: https://www.medrxiv.org/content/10.1101 ... 20037432v1
Also the link mentioning remdesivir and linking to Science mag. org https://www.sciencemag.org/news/2020/03 ... treatments is a good overview and could be missed by people that have not actually checked and read the links. This is entitled:
WHO launches global megatrial of the four most promising coronavirus treatments
Could any of these drugs hold the key to saving coronavirus disease 2019 (COVID-19) patients from serious harm or death? On Friday, the World Health Organization (WHO) announced a large global trial, called SOLIDARITY, to find out whether any can treat infections with the new coronavirus for the dangerous respiratory disease. It’s an unprecedented effort—an all-out, coordinated push to collect robust scientific data rapidly during a pandemic. The study, which could include many thousands of patients in dozens of countries, has been designed to be as simple as possible so that even hospitals overwhelmed by an onslaught of COVID-19 patients can participate.
Re: Resources Coronavirus
In 2004 I was in Zambia and witnessed the government trying to convince Zambian men that a female virgin was not the cure for AIDS...
Billboards, sides of public buses, bus stop seats all had the public service announcement that girls were not a cure.
Now that china has unleashed this virus on the World...the same Doctors and Scientists who have taken on HIV/AIDS are working to take on this virus and its mutations.
They need time and hopefully there will be breakthroughs in treatment and a vaccine down the road.
It is hard to believe that this is just going to disappear and not return next flu season.
The Infectious Disease warriors will find answers and treatments.
I saw where 2 people mistook a Koi fish product they had on hand for the malaria medication and it proved fatal.
People need to isolate and be patient.
Billboards, sides of public buses, bus stop seats all had the public service announcement that girls were not a cure.
Now that china has unleashed this virus on the World...the same Doctors and Scientists who have taken on HIV/AIDS are working to take on this virus and its mutations.
They need time and hopefully there will be breakthroughs in treatment and a vaccine down the road.
It is hard to believe that this is just going to disappear and not return next flu season.
The Infectious Disease warriors will find answers and treatments.
I saw where 2 people mistook a Koi fish product they had on hand for the malaria medication and it proved fatal.
People need to isolate and be patient.
- newkidontheblock
- Expatriate
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Re: Resources Coronavirus
Saw that on the news last night. The active ingredient is the same, but formulation different. The lady took it trying to get the active ingredient and died. All these drugs have potential bad side effects and should be give under medical direction.
For example, an elderly lady got the chloroquine + azithromycin combo and started having heart issues. Dose was then adjusted. If she took it on her own without monitoring, she could have died too.
What is known to work. Social distancing. The virus is droplet born, and doesn’t go beyond 6 feet unless aerosolized. This is the official line from the WHO. Wash hands with soap and water. Don’t touch the eyes and face before washing. Clean anything in potential contact with the virus with bleach or other agent.
Normal masks do not protect against aerosolized virus being breathed in. Only N95 masks. And full hoods to prevent eye entry. And gown, gloves, shoe covers, for the rest of the body.
What a normal mask does is prevent a person with the virus from spreading it to others. Since no one knows who is a carrier, it’s actually not bad to have everyone where a mask.
Be safe out there.
For example, an elderly lady got the chloroquine + azithromycin combo and started having heart issues. Dose was then adjusted. If she took it on her own without monitoring, she could have died too.
What is known to work. Social distancing. The virus is droplet born, and doesn’t go beyond 6 feet unless aerosolized. This is the official line from the WHO. Wash hands with soap and water. Don’t touch the eyes and face before washing. Clean anything in potential contact with the virus with bleach or other agent.
Normal masks do not protect against aerosolized virus being breathed in. Only N95 masks. And full hoods to prevent eye entry. And gown, gloves, shoe covers, for the rest of the body.
What a normal mask does is prevent a person with the virus from spreading it to others. Since no one knows who is a carrier, it’s actually not bad to have everyone where a mask.
Be safe out there.
Re: Resources Coronavirus
In view of the critical shortage of ventilators, An MIT team hopes to publish open-source designs for a low-cost ventilator
MIT researchers hope to publish open-source designs for a low-cost respirator that could potentially help COVID-19 patients struggling with critical respiratory problems. The team recently launched a website unveiling the MIT Emergency Ventilator Project, or E-Vent, which states they've submitted the device to the Food and Drug Administration for rapid review under an "Emergency Use Authorization." Last week, MIT Technology Review was informed the team intended to test the devices on pigs in recent days, though it's unclear what the results were at this stage. Article here: https://www.technologyreview.com/s/6153 ... entilator/
The MIT E-Vent is anticipated to have utility in helping free up existing supply or in life-or-death situations when there is no other option," the site adds.
Short extract:
The project dates back to about a decade ago, when a group of MIT students in the Precision Machine Design course developed a proof of principle version of the machine, working with Jussi Saukkonen of Boston University Medical Center. They published a paper on the device, but never moved forward with production.
Design paper here:
Design and Prototyping of a Low-cost Portable Mechanical Ventilator
https://web.mit.edu/2.75/projects/DMD_2 ... sseini.pdf
MIT researchers hope to publish open-source designs for a low-cost respirator that could potentially help COVID-19 patients struggling with critical respiratory problems. The team recently launched a website unveiling the MIT Emergency Ventilator Project, or E-Vent, which states they've submitted the device to the Food and Drug Administration for rapid review under an "Emergency Use Authorization." Last week, MIT Technology Review was informed the team intended to test the devices on pigs in recent days, though it's unclear what the results were at this stage. Article here: https://www.technologyreview.com/s/6153 ... entilator/
The MIT E-Vent is anticipated to have utility in helping free up existing supply or in life-or-death situations when there is no other option," the site adds.
Short extract:
The project dates back to about a decade ago, when a group of MIT students in the Precision Machine Design course developed a proof of principle version of the machine, working with Jussi Saukkonen of Boston University Medical Center. They published a paper on the device, but never moved forward with production.
Design paper here:
Design and Prototyping of a Low-cost Portable Mechanical Ventilator
https://web.mit.edu/2.75/projects/DMD_2 ... sseini.pdf
- truffledog
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Re: Resources Coronavirus
WHO launches global megatrial of the four most promising coronavirus treatments
source: https://www.sciencemag.org/news/2020/03 ... treatments
hope they find out how to best fight that virus. With all the resources engaged around the world I am confident that the solution is near. There is promising signs that early stage treatment has the best effect.
source: https://www.sciencemag.org/news/2020/03 ... treatments
hope they find out how to best fight that virus. With all the resources engaged around the world I am confident that the solution is near. There is promising signs that early stage treatment has the best effect.
work is for people who cant find truffles
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